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Gut microbiota-related metabolites (especially TMAO) may be the key mediators that mediate the changes in brain structure and function of PD mediated by gut microbiota
The reason why [semaglutide] works is not just the fact that it depresses appetite, it's that it gets insulin to work better
This balanced activation prevents receptor desensitisation that sometimes occurs with single-pathway stimulation
Increase physical activity levels gradually, aiming for at least 150 minutes of moderate-intensity exercise weekly, plus strength exercises on two days per week, as recommended by the UK Chief Medical Officers' Physical Activity Guidelines
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Key takeaways Metformin is a medication approved for treating type 2 diabetes, but healthcare providers sometimes prescribe it off-label for other conditions and weight management
